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PubMed · 12570650

Minimal model for genome evolution and growth.

Li-Ching Hsieh·Liaofu Luo·Fengmin Ji·H C Lee
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Abstract

Textual analysis of typical microbial genomes reveals that they have the statistical characteristics of a DNA sequence of a much shorter length. This peculiar property supports an evolutionary model in which a genome evolves by random mutation but primarily grows by random segmental duplication. That genomes grew mostly by duplication is consistent with the observation that repeat sequences in all genomes are widespread and intragenomic and intergenomic homologous genes are preponderant across all life forms.

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DNA, BacterialEscherichia coliEvolution, MolecularGenome, BacterialHaemophilus influenzaeMethanococcusModels, GeneticNeisseriaJournal ArticleResearch Support, Non-U.S. Gov't

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Li-Ching Hsieh, Liaofu Luo, Fengmin Ji, H C Lee. 2003-01-03. Minimal model for genome evolution and growth.. https://doi.org/10.1103/physrevlett.90.018101

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