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PubMed · 12596360

Enabling parallel protein analysis through mass spectrometry.

Bruno Domon·Kim Alving·Tao He·Terence E Ryan·Scott D Patterson
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Abstract

The targets of the majority of drugs on the market and in development are proteins, and the efficient analysis of these molecules is critical to defining targets for better therapeutic intervention. Mass spectrometry is currently the key technology for parallel protein analysis (also referred to as proteomics). In this review we will describe recent advances in mass spectrometry instrumentation, methods and applications that are likely to impact drug discovery.

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AnimalsHumansMass SpectrometryProteinsProteomicsSpectrometry, Mass, Matrix-Assisted Laser Desorption-IonizationSpectroscopy, Fourier Transform InfraredTechnology, PharmaceuticalJournal ArticleReview

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Bruno Domon, Kim Alving, Tao He, Terence E Ryan, Scott D Patterson. 2002. Enabling parallel protein analysis through mass spectrometry.. https://pubmed.ncbi.nlm.nih.gov/12596360/

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