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PubMed · 12610866

[Molecular-targeted therapy].

Tomohide Tamura
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Abstract

This article reviews the concept of molecular-targeted therapy and the current development status of molecular-targeted agents for lung cancer. Epidermal growth factor receptor inhibitors have shown promising antitumor activity against cisplatin-resistant non-small cell lung cancer in phase II trials. Appropriate clinical evaluation of these agents and collaboration with basic researchers are essential for further development.

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Antibodies, MonoclonalAntibodies, Monoclonal, HumanizedAntineoplastic AgentsCarcinoma, Non-Small-Cell LungCetuximabClinical Trials, Phase II as TopicClinical Trials, Phase III as TopicDrug Delivery SystemsEndothelial Growth FactorsErbB ReceptorsErlotinib HydrochlorideGefitinibHumansIntercellular Signaling Peptides and ProteinsLung NeoplasmsLymphokinesQuinazolinesReceptors, Vascular Endothelial Growth FactorVascular Endothelial Growth Factor AVascular Endothelial Growth FactorsJournal ArticleReview

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Tomohide Tamura. 2003. [Molecular-targeted therapy].. https://pubmed.ncbi.nlm.nih.gov/12610866/

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