DNA replication: telling time with microarrays.

Heather J McCune; Anne D Donaldson

doi:10.1186/gb-2003-4-2-204

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DNA replication: telling time with microarrays.

Heather J McCune·Anne D Donaldson

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Abstract

A long-standing hypothesis about eukaryotic DNA replication is that the late-replicating regions are transcriptionally inert and that repressing transcription delays replication initiation. But do contrasting results from yeast and a recent study in Drosophila imply that replication timing and transcriptional activity are differentially regulated in yeast and higher eukaryotes?

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Animals Cell Nucleus DNA Replication Drosophila melanogaster Oligonucleotide Array Sequence Analysis Saccharomyces cerevisiae Time Factors Transcription, Genetic Comparative Study Journal Article Review

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Heather J McCune, Anne D Donaldson. 2003-01-30. DNA replication: telling time with microarrays.. https://doi.org/10.1186/gb-2003-4-2-204

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