Visualization of ischaemic penumbra using a computed tomography perfusion method.

R T F Cheung; Pui W Cheng; Wai M Lui; Gilberto K T Leung; Ting-Yim Lee

doi:10.1159/000068824

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Visualization of ischaemic penumbra using a computed tomography perfusion method.

R T F Cheung·Pui W Cheng·Wai M Lui·Gilberto K T Leung·Ting-Yim Lee

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Abstract

A computed tomography (CT) perfusion imaging and a diffusion/perfusion magnetic resonance imaging (MRI) were performed in a 51-year-old man at 15 and 15.5 h of onset of left middle cerebral artery infarction, respectively. The established infarct, as revealed by the diffusion-weighted MRI, had low values of cerebral blood flow (CBF) and cerebral blood volume (CBV) on the CT perfusion study. The ischaemic penumbra, as reflected by the perfusion-diffusion mismatch on MRI, had reduced CBF, prolonged mean transit time (MTT) and compensated CBV. Spontaneous bleeding occurred in the medial part of the left lentiform nucleus, immediately following decompressive craniectomy. CT measurements of CBF, CBV and MTT may visualize the ischaemic penumbra and explain the site of bleeding after surgical decompression.

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Brain Ischemia Cerebrovascular Circulation Craniotomy Diffusion Humans Infarction, Middle Cerebral Artery Magnetic Resonance Imaging Male Middle Aged Neurosurgical Procedures Perfusion Tomography, X-Ray Computed Case Reports Journal Article Research Support, Non-U.S. Gov't

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R T F Cheung, Pui W Cheng, Wai M Lui, Gilberto K T Leung, Ting-Yim Lee. 2003. Visualization of ischaemic penumbra using a computed tomography perfusion method.. https://doi.org/10.1159/000068824

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