[Progress in somatic gene therapy].

Jacob Giehm Mikkelsen; Thomas Gryesten Jensen

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PubMed · 12661514

[Progress in somatic gene therapy].

Jacob Giehm Mikkelsen·Thomas Gryesten Jensen

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Abstract

Therapeutic gene transfer may constitute an alternative to current treatments. Despite promising results from animal studies common use of genes as drugs awaits improved vector efficiency and easier large-scale vector production. New developments in the field include high-capacity vectors with low immunogenicity, hybrid vectors, site-specific vector integration, RNA interference, and efficient non-viral gene transfer. In this article, we review the recent progress in somatic gene therapy with focus on vector development and current examples of clinical efficiency.

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Animals Gene Transfer Techniques Genetic Therapy Genetic Vectors Humans English Abstract Journal Article

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Jacob Giehm Mikkelsen, Thomas Gryesten Jensen. 2003-02-24. [Progress in somatic gene therapy].. https://pubmed.ncbi.nlm.nih.gov/12661514/

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