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PubMed · 12672492

Functional consequences of histone modifications.

Masayoshi Iizuka·M Mitchell Smith
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Abstract

Covalent modifications of the histone proteins have well-known roles in gene expression. Experiments reported during the past year have extended this paradigm to include roles for histone acetylation and phosphorylation in DNA double-strand break repair. In addition, new results now provide a definitive example of an acetylation histone code, whereas others reveal the workings of a charge patch mechanism. Finally, exciting research has identified new modifications, complex modification cascades, and functional links to DNA methylation and RNA interference pathways.

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AcetylationAcetyltransferasesAnimalsHistonesHumansMethylationMethyltransferasesPhosphorylationPhosphotransferasesRNASchizosaccharomycesJournal ArticleReview

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Masayoshi Iizuka, M Mitchell Smith. 2003. Functional consequences of histone modifications.. https://doi.org/10.1016/s0959-437x(03)00020-0

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