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Evolution of transcription factor function.

Cheryl C Hsia·William McGinnis
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Abstract

Functional assays in Drosophila melanogaster with orthologous transcription factors from other species suggest that changes in the protein-coding sequence may play a larger role in the evolution of transcription factor pathways than was previously believed. Interestingly, recent studies provide evidence that changes in transcription factor protein sequence can affect the regulation of only a subset of target genes, even in the same cells of a developing animal.

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AnimalsDrosophila melanogasterEvolution, MolecularPhylogenyTranscription FactorsJournal ArticleReview

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Cheryl C Hsia, William McGinnis. 2003. Evolution of transcription factor function.. https://doi.org/10.1016/s0959-437x(03)00017-0

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