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PubMed · 1269876

Piperazine hepatitis.

A N Hamlyn·J S Morris·I Sarkany·S Sherlock
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Abstract

The first reported case of piperazine toxicity resembling viral hepatitis is described in a 25-year-old woman. The illness, which was severe, occurred after administration of the drug on two separate occasions. The evidence favors a hypersensitivity mechanism rather than a direct toxic effect of piperazine or its metabolites on the liver. The humoral or cellular immune basis for such hypersensitivity has not been elucidated.

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Acute DiseaseAdultChemical PhenomenaChemical and Drug Induced Liver InjuryChemistryFemaleHumansLiverNematode InfectionsPiperazinesCase ReportsJournal Article

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A N Hamlyn, J S Morris, I Sarkany, S Sherlock. 1976. Piperazine hepatitis.. https://pubmed.ncbi.nlm.nih.gov/1269876/

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