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A novel microgravimetric DNA sensor with high sensitivity.

Tao Liu·Ji'an Tang·Meimei Han·Long Jiang
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Abstract

A novel method using an amplifier with a cantilever and gold nanoparticles successfully to extend the length of the target for the specific and high sensitive detection of DNA was reported. When the size of gold nanoparticle is 50 nm, a sensitivity of 10(-15)M for the single base mutation detection has been achieved.

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Base SequenceBiosensing TechniquesDNADNA Mutational AnalysisGoldNucleic Acid HybridizationQuartzSensitivity and SpecificityJournal ArticleResearch Support, Non-U.S. Gov't

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Tao Liu, Ji'an Tang, Meimei Han, Long Jiang. 2003-04-25. A novel microgravimetric DNA sensor with high sensitivity.. https://doi.org/10.1016/s0006-291x(03)00531-x

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