Current experience using the laboratory rat in aging studies.

C F Hollander

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PubMed · 1271744

Current experience using the laboratory rat in aging studies.

C F Hollander

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Abstract

The breeding and maintenance conditions for 2 strains of inbred rats, the WAG/Rij and BN/Bi rats, were described. The survival characteristics of these 2 strains were compared with those of 2 other experiments in which rats were kept for longevity studies under different environmental conditions of microbiologic status and diet. Data were provided on the rate and types of spontaneous tumors found in these 2 rat strains. It can be concluded that in order to obtain rats of good quality and in sufficient numbers for aging studies, breeding and raising the animals under strict SPF conditions is warranted. It is also necessary to maintain them under "clean conventional" conditions for long-term studies.

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Aging Animals Female Life Expectancy Male Rats Rats, Inbred Strains Sex Factors Comparative Study Journal Article

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C F Hollander. 1976. Current experience using the laboratory rat in aging studies.. https://pubmed.ncbi.nlm.nih.gov/1271744/

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