Nuclear lipid signalling.

Robin F Irvine

doi:10.1038/nrm1100

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Nuclear lipid signalling.

Robin F Irvine

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Abstract

During the past twenty years, evidence has accumulated for the presence of phospholipids within the nuclei of eukaryotic cells. These phospholipids are distinct from those that are obviously present in the nuclear envelope. The best characterized of the intranuclear lipids are the inositol lipids that form the components of a phosphoinositide-phospholipase C cycle. However, exactly as has been discovered in the cytoplasm, this is just part of a complex picture that involves many other lipids and functions.

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1-Phosphatidylinositol 4-Kinase Animals Cell Nucleus Growth Substances Humans Isoenzymes Lipid Metabolism Models, Biological Phosphatidylinositol 3-Kinases Phosphatidylinositol Phosphates Phosphatidylinositols Signal Transduction Type C Phospholipases Journal Article Research Support, Non-U.S. Gov't Review

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Robin F Irvine. 2003. Nuclear lipid signalling.. https://doi.org/10.1038/nrm1100

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