PubMed · 12744204
The myeloid disorders: background.
Abstract
Myeloid disorders do not usually present quite so many technical challenges to the cytogeneticist as does ALL: the chromosomes are often of a better quality, and white blood cell counts are not usually so high, except in CGL. Unlike in the chronic lymphoid disorders, there is no need for mitogens to include cell division. However, apart from the Ph in CGL, the overall frequency of detected clones is not so high. This has the consequence that a large proportion of patients is denied the diagnostic and prognostic benefit of knowing the cytogenetic abnormalities that are associated with their disease.
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John Swansbury. 2003. The myeloid disorders: background.. https://doi.org/10.1385/1-59259-363-1%3A023
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