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Chemotropic molecules: guides for axonal pathfinding and cell migration during CNS development.

Fernando de Castro
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Abstract

Different molecules (netrins, semaphorins, slits) with chemotropic functions and their receptors (neogenin, DCC, neuropilins, plexins, robos) have been identified that guide axons during development of the nervous system to establish the complex pattern of connections among a large number of neurons. These molecules have been recently identified to play a role in cell migration of the central nervous system during development.

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AnimalsAxonsCentral Nervous SystemDrosophila ProteinsEmbryo, MammalianEmbryo, NonmammalianEmbryonic and Fetal DevelopmentHumansNerve Growth FactorsNerve Tissue ProteinsNeural PathwaysSemaphorinsJournal ArticleResearch Support, Non-U.S. Gov'tReview

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Fernando de Castro. 2003. Chemotropic molecules: guides for axonal pathfinding and cell migration during CNS development.. https://doi.org/10.1152/nips.01414.2002

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