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Herpes simplex virus latency-associated transcript gene function.

Jennifer R Kent·Wen Kang·Cathie G Miller·Nigel W Fraser
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Abstract

A major area of interest in the study of herpes simplex virus type 1 (HSV-1) involves the persistence of the virus within a latent state in neuronal cells of infected humans. The latency-associated transcripts (LATs) are believed to play a key role during HSV-1 latency. This review will discuss the most recent findings on the involvement of the LAT region with apoptotic pathways and how this relates to other potential functions of the LATs.

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AnimalsApoptosisGene Expression Regulation, ViralGenes, OverlappingGenes, ViralHerpesvirus 1, HumanHumansIntronsMiceNeuronsRNA, ViralRabbitsTranscription, GeneticVirus LatencyJournal ArticleReview

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Jennifer R Kent, Wen Kang, Cathie G Miller, Nigel W Fraser. 2003. Herpes simplex virus latency-associated transcript gene function.. https://doi.org/10.1080/13550280390200994

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