Low-grade malignant eccrine spiradenoma with systemic metastases.

Niamh Leonard; David Smith; Paul McNamara

doi:10.1097/00000372-200306000-00011

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Low-grade malignant eccrine spiradenoma with systemic metastases.

Niamh Leonard·David Smith·Paul McNamara

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Abstract

Malignant eccrine spiradenoma (MES) is a very rare tumor. Tumors can be low grade or high grade. There are nine cases in the literature with systemic metastases. Of these, only one was low grade; the others had obvious features of high-grade malignancy such as pleomorphism, increased mitoses, and abnormal mitoses. Low grade MESs are more difficult to diagnose and are said to have a better prognosis. We report an additional case of low-grade MES with systemic metastases. It had a monotonous appearance with few mitotic figures and minimal pleomorphism. Vascular invasion was seen in both cases of low-grade MES and may be an important prognostic feature.

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Adenocarcinoma Adenoma, Sweat Gland Biopsy Bone Neoplasms Fatal Outcome Female Humans Middle Aged Neoplasm Metastasis Sweat Gland Neoplasms Case Reports Journal Article Review

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Niamh Leonard, David Smith, Paul McNamara. 2003. Low-grade malignant eccrine spiradenoma with systemic metastases.. https://doi.org/10.1097/00000372-200306000-00011

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