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PubMed · 12776587

[Study on the preparation of venenum bufonis beta-cyclodextrin inclusion complexes].

Tao Guo·Hong-tao Song·Ming-hong Zhao·Ru-hua Zhang·Xian Li
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Abstract

OBJECTIVE: To study the preparation of Venenum Bufonis beta-cyclodextrin inclusion complexes. METHOD: An optimal condition was established by the uniform design. Under the optimal conditions the Venenum Bufonis beta-cyclodextrin inclusion complexes were prepared with 5 different methods. RESULT: The ball grinding method was superior to other four methods. The bufadienolide inclusion rate of Venenum Bufonis beta-cyclodextrin prepared with ball grinding method was 85.42%. CONCLUSION: Ball grinding method is the best method for the preparation of Venenum Bufonis beta-cyclodextrin inclusion complexes.

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Amphibian VenomsAnimalsBufanolidesBufo bufoCholenesCyclodextrinsDrug CarriersDrug StabilityMateria MedicaSolubilityTechnology, Pharmaceuticalbeta-CyclodextrinsEnglish AbstractJournal ArticleResearch Support, Non-U.S. Gov't

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Tao Guo, Hong-tao Song, Ming-hong Zhao, Ru-hua Zhang, Xian Li. 2002. [Study on the preparation of venenum bufonis beta-cyclodextrin inclusion complexes].. https://pubmed.ncbi.nlm.nih.gov/12776587/

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