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Ventricular function abnormalities in active rheumatoid arthritis: a Doppler echocardiographic study.

Funda Levendoglu·Ahmet Temizhan·Hatice Ugurlu·Ayse Ozdemir·Mehmet Yazici
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Abstract

OBJECTIVE: The aim of the present study was to evaluate cardiac involvement in patients with active rheumatoid arthritis (RA). METHODS: Forty patients with active RA participated. All were submitted to standard Doppler echocardiography and myocardial performance index (MPI) grading. RESULTS: There were left and right ventricular diastolic function abnormalities in RA patients. Left ventricular MPI was also significantly higher than in controls ( P<0.05). A relationship was found between left ventricular early diastolic (E)/atrial (A) flow velocities (E/A ratio), isovolumic relaxation time (IRT), and disease duration ( r=-0.47 and P=0.002, r=0.618 and P=0.000, respectively). CONCLUSION: Diastolic function was impaired in both ventricles in patients with active RA. There was a direct relationship between some of the parameters of left ventricular diastolic function and disease duration as well. These findings suggest a subclinical myocardial involvement in RA patients.

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Arthritis, RheumatoidDiastoleEchocardiography, DopplerFemaleHealth StatusHeartHumansMaleMiddle AgedSeverity of Illness IndexVentricular Dysfunction, LeftVentricular Dysfunction, RightVentricular FunctionJournal Article

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Funda Levendoglu, Ahmet Temizhan, Hatice Ugurlu, Ayse Ozdemir, Mehmet Yazici. 2003-06-19. Ventricular function abnormalities in active rheumatoid arthritis: a Doppler echocardiographic study.. https://doi.org/10.1007/s00296-003-0342-z

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