UniqueProt: Creating representative protein sequence sets.

Sven Mika; Burkhard Rost

doi:10.1093/nar/gkg620

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UniqueProt: Creating representative protein sequence sets.

Sven Mika·Burkhard Rost

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Abstract

UniqueProt is a practical and easy to use web service designed to create representative, unbiased data sets of protein sequences. The largest possible representative sets are found through a simple greedy algorithm using the HSSP-value to establish sequence similarity. UniqueProt is not a real clustering program in the sense that the 'representatives' are not at the centres of well-defined clusters since the definition of such clusters is problem-specific. Overall, UniqueProt is a reasonable fast solution for bias in data sets. The service is accessible at http://cubic.bioc.columbia.edu/services/uniqueprot; a command-line version for Linux is downloadable from this web site.

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Algorithms Internet Protein Structure, Tertiary Proteins Sequence Alignment Sequence Analysis, Protein Software User-Computer Interface Journal Article Research Support, U.S. Gov't, P.H.S.

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Sven Mika, Burkhard Rost. 2003-07-01. UniqueProt: Creating representative protein sequence sets.. https://doi.org/10.1093/nar%2Fgkg620

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