[EBV in malignant lymphomas].

S Handt; K Hoffmeister; K Wilgenbus; C J Kirkpatrick

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PubMed · 1283257

[EBV in malignant lymphomas].

S Handt·K Hoffmeister·K Wilgenbus·C J Kirkpatrick

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Abstract

PCR and in-situ-Hybridization were used to detect EBV-DNA within Hodgkin- and Non-Hodgkin-Lymphomas. By the use of primers for the Bam H1 W fragment we could show EBV-DNA to be associated with 45% Hodgkin- and 25% T-Lymphomas, whereas we could not find EBV-DNA within B-Lymphomas. In about one third of the PCR-positive cases we could localize EBV-DNA mostly in the tumor cell nuclei by in-situ-hybridization.

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Base Sequence Herpesvirus 4, Human Hodgkin Disease Humans In Situ Hybridization Lymphoma Lymphoma, Non-Hodgkin Molecular Sequence Data Oligonucleotide Probes Polymerase Chain Reaction English Abstract Journal Article

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S Handt, K Hoffmeister, K Wilgenbus, C J Kirkpatrick. 1992. [EBV in malignant lymphomas].. https://pubmed.ncbi.nlm.nih.gov/1283257/

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