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PubMed · 12833653

PEG-sTNF-RI. Amgen.

Cynthia Darlington
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Abstract

PEGylated soluble tumor necrosis factor-receptor type I (PEG-sTNF-RI) is a second-generation TNF-binding protein in development by Amgen as a potential treatment for rheumatoid arthritis (RA). PEG-sTNF-RI is an optimized, monomeric form of the first-generation molecule, TNFbp. By 1999, PEG-sTNF-RI was undergoing phase II trials for RA, and these trials were ongoing in March 2003.

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AnimalsAntigens, CDAntirheumatic AgentsArthritis, RheumatoidClinical Trials as TopicHumansPolyethylene GlycolsReceptors, Tumor Necrosis FactorReceptors, Tumor Necrosis Factor, Type ITechnology, PharmaceuticalJournal ArticleReview

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Cynthia Darlington. 2003. PEG-sTNF-RI. Amgen.. https://pubmed.ncbi.nlm.nih.gov/12833653/

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