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PubMed · 12842028

Regeneration: every clot has a thrombin lining.

Malcolm Maden
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Abstract

Why do some amphibian organs regenerate and others do not? And why do most mammalian organs not regenerate? New work on lens regeneration indicates that the answer lies in the need for cells to dedifferentiate first, and that what makes them dedifferentiate may be the presence of thrombin in combination with cellular clotting factors.

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AnimalsCell DifferentiationLens, CrystallineModels, BiologicalRegenerationRetinoblastoma ProteinThrombinCaudataJournal ArticleReview

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Malcolm Maden. 2003-07-01. Regeneration: every clot has a thrombin lining.. https://doi.org/10.1016/s0960-9822(03)00444-5

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