Technology evaluation: GEM-231, Hybridon.

Pollen K F Yeung

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PubMed · 12870443

Technology evaluation: GEM-231, Hybridon.

Pollen K F Yeung

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Abstract

GEM-231 (HYBO-165) is an 18mer hybrid oligonucleotide under development by Hybridon for the potential treatment of cancer. Phase I/II dose-escalation trials of GEM-231 in combination with paclitaxel and docetaxel were ongoing in March 2002. At this time, a phase I/II trial of GEM-231 in combination with irinotecan (CPT-11) was initiated in patients with solid tumors. As of February 2003, Hybridon planned to initiate phase II trials in 2003.

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Animals Antineoplastic Agents Cell Line Clinical Trials, Phase I as Topic Clinical Trials, Phase II as Topic Humans Neoplasms Oligonucleotides Evaluation Study Journal Article

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Pollen K F Yeung. 2003. Technology evaluation: GEM-231, Hybridon.. https://pubmed.ncbi.nlm.nih.gov/12870443/

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