[Hemodynamic factors].

Takehide Ogihara; Tomoichiro Asano

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PubMed · 12877069

[Hemodynamic factors].

Takehide Ogihara·Tomoichiro Asano

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Abstract

It is well-known that hypertension often coexists with diabetes. Based on previous reports, it appears that insulin resistance is promoted by hypertension and that hypertension is promoted by insulin resistance. In this review, we discuss hemodynamic factors underlying insulin resistance and hypertension. In addition, the insulin resistance seen in three hypertensive rat models (the high salt-fed Sprague-Dawley rat, the Dahl salt-sensitive rat and the chronically angiotensin II-infused rat) are presented. The findings presented suggest the importance of developing new therapeutic approaches (e.g., potassium supplementation and anti-oxidant administration) to the management of insulin resistance and hypertension.

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Angiotensin II Animals Diabetes Mellitus Disease Models, Animal Humans Hypertension Insulin Insulin Resistance Oxidative Stress Rats Rats, Inbred Dahl Rats, Sprague-Dawley Signal Transduction English Abstract Journal Article Review

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Takehide Ogihara, Tomoichiro Asano. 2003. [Hemodynamic factors].. https://pubmed.ncbi.nlm.nih.gov/12877069/

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