Cilengitide Merck.

Jeffrey W Smith

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PubMed · 12901235

Cilengitide Merck.

Jeffrey W Smith

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Abstract

Merck KGaA is developing cilengitide, the lead in a series of integrin antagonists with anti-angiogenic activities, for the potential treatment of a variety of cancer types. The National Cancer Institute is conducting clinical trials of cilengitide. In October 1999, phase II trials in non-small-cell lung cancer (as a monotherapy) and pancreatic cancer (in combination with gemcitabine) were initiated. These were ongoing in February 2002, by which time, a phase I trial and a phase I/II trial in glioblastoma were underway.

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Angiogenesis Inhibitors Animals Clinical Trials as Topic Drugs, Investigational Humans Neoplasms Snake Venoms Technology, Pharmaceutical Journal Article Review

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Jeffrey W Smith. 2003. Cilengitide Merck.. https://pubmed.ncbi.nlm.nih.gov/12901235/

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