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Improving sensitivity by large-volume sample stacking using the electroosmotic flow pump to analyze some nonsteroidal anti-inflammatory drugs by capillary electrophoresis in water samples.

Alba Macià·Francesc Borrull·Carme Aguilar·Marta Calull
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Abstract

Large-volume sample stacking using the electroosmotic flow (EOF) pump (LVSEP) has been used to analyze some nonsteroidal anti-inflammatory drugs (NSAIDs) in water samples. With methanol as the run buffer solvent to suppress the EOF, sensitivity was enhanced by 80-100-fold. The sample for the analysis of real water sample was pretreated by solid-phase extraction (SPE). When the method was based on off-line SPE-LVSEP-CE, sensitivity improved by as much as 1000 times.

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Anti-Inflammatory Agents, Non-SteroidalBuffersCalibrationElectrophoresis, CapillaryOsmosisReproducibility of ResultsSolventsWater Pollutants, ChemicalJournal ArticleResearch Support, Non-U.S. Gov't

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Alba Macià, Francesc Borrull, Carme Aguilar, Marta Calull. 2003. Improving sensitivity by large-volume sample stacking using the electroosmotic flow pump to analyze some nonsteroidal anti-inflammatory drugs by capillary electrophoresis in water samples.. https://doi.org/10.1002/elps.200305542

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