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PubMed · 12956972

Epithelial migration: open your eyes to c-Jun.

Richard Grose
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Abstract

Tissue-specific removal of c-jun from epidermal cells in mice leads to a failure of eyelid fusion during embryogenesis and reveals roles for c-Jun in wound repair and tumorigenesis in adult skin. This has provided a definitive test of the in vivo function of AP-1 signalling and shown that EGF signalling is key to all of c-Jun's roles in the epidermis.

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AnimalsEpidermal Growth FactorEpidermisEpitheliumEyelidsFeedback, PhysiologicalGenes, junMiceMice, KnockoutSignal TransductionTranscription Factor AP-1Journal ArticleReview

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BibTeXRIS

Richard Grose. 2003-09-02. Epithelial migration: open your eyes to c-Jun.. https://doi.org/10.1016/s0960-9822(03)00607-9

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