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Interleukin 10: an overview.

D Rennick·D Berg·G Holland
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Abstract

Since the original description of interleukin-10, a wealth of information concerning its biological properties has been gathered. Studies in vitro have rapidly identified both immunostimulatory and immunosuppressive activities for IL-10. Based on these findings, in vivo studies were initiated in a variety of animal disease models to assess the importance of these activities. This review will summarize the pleiotropic properties of IL-10 and will survey current research regarding the potential of IL-10 to regulate acute and chronic inflammatory reactions.

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AnimalsHematopoiesisHematopoietic Stem CellsHumansInterleukin-10T-Lymphocytes, Helper-InducerJournal ArticleReview

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D Rennick, D Berg, G Holland. 1992. Interleukin 10: an overview.. https://doi.org/10.1016/0955-2235(92)90020-i

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