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Fructose 2,6-bisphosphate in developing rat brain.

S Ambrosio·F Ventura·R Bartrons
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Abstract

Fructose 2,6-bisphosphate (Fru-2,6-P2) levels and 6-phosphofructo-1-kinase and 6-phosphofructo-2-kinase activities have been studied in rat brain during development from embryonal to adult state. Fru-2,6-P2 increases slightly from day 16 of gestation, reaching a maximum 24 h after birth, remaining quite constant during postnatal development. In contrast with 6-phosphofructo-1-kinase, which increases progressively after the first week of age, 6-phosphofructo-2-kinase remains unaltered throughout the period studied. The role of Fru-2,6-P2 in controlling cerebral glycolysis is discussed.

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AnimalsBrainBrain ChemistryFemaleFructosediphosphatesPhosphofructokinase-1Phosphofructokinase-2PhosphotransferasesRatsRats, Inbred StrainsJournal ArticleResearch Support, Non-U.S. Gov't

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S Ambrosio, F Ventura, R Bartrons. 1992-04-24. Fructose 2,6-bisphosphate in developing rat brain.. https://doi.org/10.1016/0165-3806(92)90092-b

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