Postnatal change in a Ca(2+)-mediated decrease in (Na+ + K+)-ATPase activity in rat brain slices.

T Matsuda; I Shimizu; A Baba

doi:10.1016/0006-8993(92)90499-y

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Postnatal change in a Ca(2+)-mediated decrease in (Na+ + K+)-ATPase activity in rat brain slices.

T Matsuda·I Shimizu·A Baba

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Abstract

The treatment of brain slices from immature rats with veratrine and monensin did not cause any change in (Na+ + K+)-adenosine triphosphatase (ATPase) activity or [3H]ouabain binding in membranes prepared from the slices, though these reagents remarkably stimulated Ca2+ uptake in the slices. Exposure of the slices from adult rats to a glucose-free, hypoxic or both glucose-free and hypoxic medium resulted in a decrease in the enzyme activity, but the enzyme from immature rats was resistant to the conditions.

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Animals Brain Calcium In Vitro Techniques Male Monensin Ouabain Rats Rats, Inbred Strains Sodium-Potassium-Exchanging ATPase Veratrine Journal Article Research Support, Non-U.S. Gov't

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T Matsuda, I Shimizu, A Baba. 1992-02-14. Postnatal change in a Ca(2+)-mediated decrease in (Na+ + K+)-ATPase activity in rat brain slices.. https://doi.org/10.1016/0006-8993(92)90499-y

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