PubMed · 13338216
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G C TYLER. 1956. Colon polyps and unexplained rectal bleeding.. https://pubmed.ncbi.nlm.nih.gov/13338216/
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BACKGROUND: In 1996, the Association of Directors of Anatomic and Surgical Pathology (ADASP) published recommendations for colon carcinoma reporting. Since this publication, no study has evaluated physician practice in relation to these recommendations. The objectives of the current study were to describe pathology reporting for colon carcinoma, evaluate potential variations in reporting, and identify areas for improvement. METHODS: Data were obtained from a population-based study of incident colon carcinoma in 33 counties in North Carolina between 1997 and 2000. All subjects with surgically resected colon carcinoma of tumor stage T2-T4 with available surgical pathology reports were eligible for inclusion in the current analysis. The authors reviewed pathology reports for adherence to recommendations of the ADASP. RESULTS: Four hundred thirty-eight pathology reports were included for analysis. Adherence to ADASP recommendations was < 90% for descriptions of how specimen was received (68%), how specimen was identified (71%), macroscopic depth of penetration (82%), appearance of serosa adjacent to tumor (50%), and status of residual bowel (73%). All other criteria were reported in > 90% of patients. Teaching hospital and contract pathology laboratories had greater adherence to recommendations, compared with community hospital laboratories. Hospitals with the highest colon carcinoma case volume demonstrated greater adherence to recommendations, compared with low-volume hospitals. CONCLUSIONS: Pathology reports were effective in communicating most pertinent findings from surgically resected colon carcinoma specimens. Omissions of some critical characteristics did occur, however, and significant variability in reporting existed based on laboratory affiliation and hospital case volume.
We present a method for creating a network of gene co-occurrences from the literature and partitioning it into communities of related genes. The way in which our method identifies communities makes it likely that the component genes of each community will be related by their function. The method processes a large database of article abstracts, synthesizing information from many sources to shed light on groups of genes that have been shown to interact. It is a tool to be used by researchers in the biomedical sciences to swiftly search for known interactions and to provide insight into unexplored connections. The partitioning procedure is designed to be particularly applicable to large networks in which individual nodes may play a role in more than one community. In this paper, we explain the details of the method, in particular the partitioning process. We also apply the method to produce communities of genes related to colon cancer and show that the results are useful.
Colorectal cancers profited much from the progress of the imagery, which have occurred since a score of years. The imagery by magnetic resonance, in particular, supplanted the porto-scanner in the evaluation of hepatic metastases of colorectal cancers requiring a surgery. In the field of the assessment of the metastatic disease, like in the event of suspicion of recurrence of a cancer of the rectum, the functional imagery with tomography by emission of positons also represents a major projection whose indications should grow progressively with the equipment of the territory. The echo-endoscopy, whose advent is older, allows a very precise exploration of the loco-regional extension of cancers of the rectum, indication for which it was still threatened by no other examination. Lastly, and whereas its place largely remains to be defined, images obtained by virtual coloscopy, are very impressive. It however will be necessary, in the years to come, to precisely evaluate the interest of this new method of imagery in the diagnosis of colorectal tumors, or in the follow-up of certain patients.