PubMed · 13340756
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H KASER. 1956. Peromelia.. https://pubmed.ncbi.nlm.nih.gov/13340756/
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Acardiac twinning is the most extreme form of twin-twin transfusion syndrome occurring in monzygotic twin pregnancies with monochorionic placentation. A case of acardiac amorphous foetus, occurring in association with spontaneously conceived triplet pregnancy, diagnosed on ultrasound in early second trimester is described and its antenatal management and brief review of literature discussed.
Chang and Eng, the two young men who would eventually be known around the world as the 'original' Siamese twins, arrived in the West in 1829. They were brought to the West to be examined by medical men and to be exhibited to the general public. Throughout the 19th century in Britain and the US, 'monstrosities' such as Chang and Eng, as well as a host of other people with unusual anatomies, were considered both spectacles worthy of public display and edifying medical subjects with the potential to build on medical knowledge. The unique case of Chang and Eng illustrates that the boundary between what is of legitimate medical interest and what is considered merely spectacle is often blurred.
Acardiac twinning is a very rare complication of multiple pregnancy. The authors present the neuropathological and anatomopathological description of the twins of the multiple pregnancy complicated by the acardiac foetus and terminated at 26 weeks of gestation. An anatomopathological examination of the "normal" twin showed hyaline membrane syndrome, cardiomegaly and hepatomegaly. Neuropathologically, numerous hypoxic-ischaemic lesions, most likely associated with haemodynamic disorders during pregnancy as well as less pronounced perinatal changes were revealed. The acardiac foetus, classified as acardius acephalus, demonstrated the presence of some abdominal organs and a histologically well-developed spinal cord. In view of the neuropathological changes, monitoring "normal" twins for discreet pathological central nervous system signs, which may be similar in character to those described, may play a significant role.