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Formation of lipoperoxide in isolated sciatic nerve by chinoform-ferric chelate.

Y Yagi·M Matsuda·K Yagi
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Abstract

Effects of chinoform and chinoform-ferric chelate on formation of lipoperoxide in isolated sciatic nerve were investigated. Free chinoform did not increase the lipoperoxide level, while chinoform-ferric chelate significantly increased it. Assuming that the lipoperoxide formed denatures the associated protein in the nerve, the effect of chinoform-ferric chelate could explain, at least partly, the demyelination of nerve tissues caused by massive doses of chinoform.

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AnimalsChelating AgentsClioquinolFerric CompoundsIronLipid MetabolismMalePeroxidesRabbitsSciatic NerveJournal Article

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Y Yagi, M Matsuda, K Yagi. 1976. Formation of lipoperoxide in isolated sciatic nerve by chinoform-ferric chelate.. https://doi.org/10.1007/bf02003759

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