PubMed Health⌕ Search
Home/Archive/PubMed

PubMed · 13435902

Optical methods for measuring nucleoprotein and nucleic acid concentrations.

S W ENGLANDER·H T EPSTEIN
View original source ↗Export metadata ↓

Abstract

The source did not provide an abstract. Follow the original record for more information.

Explore related subjects

Nucleic AcidsNucleoproteinsNUCLEIC ACIDS/determinationNUCLEOPROTEINS/determinationJournal Article

Keep this discovery

Explore connections, maps & timelines

BibTeXRIS

S W ENGLANDER, H T EPSTEIN. 1957. Optical methods for measuring nucleoprotein and nucleic acid concentrations.. https://doi.org/10.1016/0003-9861(57)90334-x

Cite the original work for its findings. Save a collection to share your selection of sources.

KEEP EXPLORING

Related citations

PubMed2006

Nucleotides and nucleic acids: a source of inspiration for the development of new, phosphorus-centered functional groups.

Synthetic methodologies aiming at the creation of new phosphorus-centered functional groups are reported, as well as applications to the field of nucleotide chemistry. Thus, difluorophosphonothioate-based, ionic reagents 3b and 3d are shown to allow the stereocontrolled and efficient synthesis of phosphonodifluoromethyl analogues of nucleoside-3'-phosphates. An alternate, radical approach describes the use of hypophosphorous acid to stereoselectively link two furanosyl units in positions 3 and 5, and to provide an access to alpha,alpha-difluoro-H-phosphinates. These intermediates are shown to be precursors to the corresponding fluorinated phosphonic acids, phosphonothioic acids and variously substituted phosphinates.

Nucleic Acids↗
PubMed2005

Nucleic Acid analysis by fourier transform ion cyclotron resonance mass spectrometry at the beginning of the twenty-first century.

Mass spectrometers measure an intrinsic property (i.e., mass) of a molecule, which makes it an ideal platform for nucleic acid analysis. Importantly, the unparalleled capabilities of Fourier transform ion cyclotron resonance (FT-ICR) mass spectrometry further extend its usefulness for nucleic acid analysis. The beginning of the twenty-first century has been marked with notable advances in the field of FT-ICR mass spectrometry analysis of nucleic acids. Some of these accomplishments include fundamental studies of nucleic acid properties, improvements in sample clean up and preparation, better methods to obtain higher mass measurement accuracy, analysis of noncovalent complexes, tandem mass spectrometry, and characterization of peptide nucleic acids. This diverse range of studies will be presented herein.

Nucleic Acids↗