[Experimental data on epithelial factors modulating bronchial reactivity].

I Hăulică; M Nechifor; D Ungureanu; O Bălţatu; D Boişteanu

PubMed · 1344853

[Experimental data on epithelial factors modulating bronchial reactivity].

I Hăulică·M Nechifor·D Ungureanu·O Bălţatu·D Boişteanu

Abstract

A tracheobronchial smooth muscle reactivity study on isolated guinea pig tracheal rings was done. The presence of two different factors active on smooth muscle, an inhibiting one, as well as an activating one was identified. Generated on different pathways, the epithelial derived relaxing factor is a cyclooxygenase dependent prostaglandin, while the activating epithelial factor seems to be a thromboxane derivate.

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Animals Biological Factors Bronchi Cyclooxygenase Inhibitors Epithelium Guinea Pigs In Vitro Techniques Muscle Contraction Muscle, Smooth Thromboxane-A Synthase Trachea Comparative Study English Abstract Journal Article

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I Hăulică, M Nechifor, D Ungureanu, O Bălţatu, D Boişteanu. [Experimental data on epithelial factors modulating bronchial reactivity].. https://pubmed.ncbi.nlm.nih.gov/1344853/

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