Taurine uptake into chick B cells.

D W Porter; W G Martin

doi:10.3181/00379727-199-43354

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Taurine uptake into chick B cells.

D W Porter·W G Martin

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Abstract

The objective of the present study was to determine whether chick B cells possess a specific transport system for taurine. The Bursa of Fabricius was isolated from newly hatched to 6-week-old chicks and an enriched fraction (86.2%) of B cells was isolated. The chick B cells maintained a high intracellular taurine concentration (0.8-1.12 mM) that decreased with age. The B cells exhibited carrier-mediated and simple diffusion uptake components, but only the carrier-mediated component increased with age. Inhibitor studies indicated taurine uptake was sodium and energy dependent. The data demonstrate that chick B cells possess a specialized taurine transport system and the activity of this system changes during posthatch B cell development.

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Aging Analysis of Variance Animals Animals, Newborn B-Lymphocytes Biological Transport Bursa of Fabricius Chickens Chromatography, High Pressure Liquid Cysteine Dinitrophenols Neurotransmitter Agents Ouabain Sodium Taurine beta-Alanine Journal Article Research Support, U.S. Gov't, Non-P.H.S.

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D W Porter, W G Martin. 1992. Taurine uptake into chick B cells.. https://doi.org/10.3181/00379727-199-43354

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