PubMed · 13480073
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I L BENNETT, E W HOOK. 1957. Fever of unknown origin.. https://doi.org/10.1016/s0011-5029(57)80007-8
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Hyper-IgD and periodic fever syndrome (HIDS) is a hereditary autoinflammatory syndrome, characterized by recurrent inflammatory attacks. Treatment of HIDS is difficult. Recently, the IL-1ra analogue anakinra was reported to be successful in aborting the IgD inflammatory attacks in a vaccination model. We report a clinical case of spectacular reduction of febrile attacks in a severe HIDS patient.