[Endogenous prostaglandins and decrease of sensitivity to noradrenaline in the rat].

J Damas; J Lecomte

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PubMed · 134822

[Endogenous prostaglandins and decrease of sensitivity to noradrenaline in the rat].

J Damas·J Lecomte

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Abstract

In the Rat, desensitization to noradrenaline induced by perfusion of large doses of noradrenaline (0.5 to 0.75 mug/mn/100 g), is not suppressed by indomethacine (1 to 5 mg/100 g). Synthesis and release of endogenous prostaglandins of the PGE group are not the cause of the desensitization.

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J Damas, J Lecomte. 1976. [Endogenous prostaglandins and decrease of sensitivity to noradrenaline in the rat].. https://pubmed.ncbi.nlm.nih.gov/134822/

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