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Gamma interferon modifies CD4+ subset expression in murine candidiasis.

L Romani·E Cenci·A Mencacci·R Spaccapelo·U Grohmann·P Puccetti·F Bistoni
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Abstract

A single injection of monoclonal antibody to gamma interferon administered in conjunction with a live Candida albicans yeast cell vaccine resulted in the detection of nonprotective Th2 rather than protective Th1 responses and altered the early expression of interleukin 4 and gamma interferon mRNA in CD4+ cells.

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AnimalsAntigens, FungalCD4-Positive T-LymphocytesCandida albicansCandidiasisGene ExpressionHypersensitivity, DelayedImmunity, CellularInterferon-gammaInterleukin-4MiceRNA, MessengerT-Lymphocytes, Helper-InducerJournal ArticleResearch Support, Non-U.S. Gov't

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L Romani, E Cenci, A Mencacci, R Spaccapelo, U Grohmann, P Puccetti, F Bistoni. 1992. Gamma interferon modifies CD4+ subset expression in murine candidiasis.. https://doi.org/10.1128/iai.60.11.4950-4952.1992

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