Programmed cell death and AIDS: from hypothesis to experiment.

J C Ameisen

doi:10.1016/0167-5699(92)90086-m

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Programmed cell death and AIDS: from hypothesis to experiment.

J C Ameisen

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Abstract

Here, Jean Claude Ameisen discusses new findings supporting the hypothesis that abnormal induction of programmed cell death (PCD) is relevant to AIDS pathogenesis. Recent evidence also suggests that the prevention of PCD is a factor in oncogenesis. Together, these ideas provide a framework for the reinterpretation of cell survival disorders in terms of PCD dysregulation, and suggest that in vivo control of cell signalling has wide-ranging therapeutic potential.

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Acquired Immunodeficiency Syndrome Apoptosis CD4-Positive T-Lymphocytes Cell Death HIV Infections Humans Signal Transduction T-Lymphocytes, Regulatory Journal Article Review

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J C Ameisen. 1992. Programmed cell death and AIDS: from hypothesis to experiment.. https://doi.org/10.1016/0167-5699(92)90086-m

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