PubMed · 13667807
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H A BARO, J R ECHEVERRIA, E P DE BARO. 1958-11-21. [The heart & hyperthyroidism].. https://pubmed.ncbi.nlm.nih.gov/13667807/
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Accurate quantification and timing of regional myocardial function allows early identification of dysfunction, and therefore becomes increasingly important for clinical risk assessment, patient management, and evaluation of therapeutic efficacy. For this purpose, the application of tissue Doppler echocardiography has rapidly increased. However, echocardiography has some major inherent limitations. Cardiovascular magnetic resonance imaging with tissue tagging provides highly reproducible data on myocardial function, not only in longitudinal and radial directions, but also in the circumferential direction. Because of the development of faster imaging protocols, improved temporal resolution, less time-consuming postprocessing procedures, and the potential of quantifying myocardial deformation in 3 dimensions at any point in the heart, this technique may serve as an alternative for tissue Doppler echocardiography and is now ready for more widespread clinical use. This review discusses the clinical use of cardiovascular magnetic resonance tissue tagging for quantitative assessment of regional myocardial function, thereby underlining the specific features and emerging role of this technique.
We describe a new segmentation method of dynamic nuclear medicine images based on the cross-Psi(B)-energy operator. Psi(B) is a nonlinear measure which quantifies the interaction between two time-signals including their first and second derivatives. Similarity measure, noted SimilB, between the time activity curve (TAC) of each pixel and the mean value of the TACs of a reference region of the scintigraphic image series is calculated. The resulting SimilB map is a functional image representing regions with different temporal dynamics. Some new properties of Psi(B) are presented. Particularly, we show that Psi(B) as a similarity measure is robust to both scale and time shift. The proposed method is applied to nuclear cardiac sequences for visualization and analysis of the ventricular emptying pattern, which may be useful in studying motion or conduction abnormalities. Results of a normal subject and four patients with abnormal ventricular contraction patterns are presented to highlight the suitability of this operator for studying non-stationary TAC series.