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Antisense oligonucleotides for therapeutic intervention.

S L Eck·G J Nabel
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Abstract

Advances have been made in defining the best target sequences for use in antisense oligonucleotide technology, and new chemical derivatives of oligonucleotides are being investigated. Although the potential use of antisense oligonucleotide agents in the treatment of neoplastic, viral and parasitic diseases continues to be explored, they are not yet suitable for administration to humans for reasons that are discussed.

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AnimalsAntineoplastic AgentsAntiviral AgentsHumansOligonucleotides, AntisenseParasitic DiseasesJournal ArticleReview

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S L Eck, G J Nabel. 1991. Antisense oligonucleotides for therapeutic intervention.. https://doi.org/10.1016/s0958-1669(05)80128-4

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