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PubMed · 1369349

Receptor-based assays.

A D Strosberg·J E Leysen
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Abstract

Receptor-based assays have benefitted from the newest advances in biotechnology and electronics in three main ways: genetically engineered cells expressing single receptor subtypes have been developed for many natural and synthetic ligands; assays have been designed which take advantage of a variety of signals triggered in cells by binding, or inhibition of binding, of ligands to surface-bound receptors; and radiolabelled ligand assays have been considerably improved and simplified by novel electronic devices.

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AnimalsBeta ParticlesFiltrationHumansLigandsPhosphorylationReceptors, Cell SurfaceTyrosineJournal ArticleResearch Support, Non-U.S. Gov'tReview

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A D Strosberg, J E Leysen. 1991. Receptor-based assays.. https://doi.org/10.1016/0958-1669(91)90058-d

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