PubMed · 13698837
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A S FENN, N KUTAR. 1960. Functioning carcinoid tumours.. https://pubmed.ncbi.nlm.nih.gov/13698837/
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BACKGROUND: Testicular tumors in general can be classified as seminoma, embryonal carcinoma, teratocarcinoma, choriocarcinoma, and mixed tumors. Nevertheless, other histological types may also be observed. In rare cases, primary or secondary neuroendocrine tumors derived from chromaffine cells can be observed in the testicle. CASE REPORT: A 51-year-old patient was hospitalized on account of a two-month-old painless tumescence of the right testicle. Radical orchiectomy revealed a solid, inhomogeneous intratesticular tumor 3 cm in diameter. Pathohistological findings and immunohistochemical staining with different neuroendocrine markers revealed a testicular carcinoid classified as pT1. The excretion of 5-hydroxyindole-acetic acid (5-HIAA) was within the normal range. No further carcinoid tumor site was found. CONCLUSIONS: In case of a testicular carcinoid, exclusion of a primary carcinoid tumor site in other organs is mandatory.
Primary carcinoid tumors originating in a normal kidney are exceptionally rare. We describe a case of a 52-year-old woman who presented with vague back pain and was found to have a 4-cm mass in the medial aspect of the left kidney. Radical nephrectomy and retroperitoneal lymphadenectomy were performed. Histopathology revealed a typical carcinoid tumor with 1 out of 17 lymph nodes involved. She has no evidence of recurrence or metastasis on 7-month follow-up.
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