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PubMed · 1372838

Integrin expression by human articular chondrocytes.

D M Salter·D E Hughes·R Simpson·D L Gardner
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Abstract

Expression of integrins, a family of cell adhesion proteins, by human articular cartilage chondrocytes in vivo has been studied by immunohistological techniques using cryostat sections and a panel of anti-integrin monoclonal antibodies. Chondrocytes strongly expressed beta 1 and alpha 5 integrin subunits, known to form the classical fibronectin receptor, VLA-5, strongly. alpha 1 was expressed more weakly and variably; alpha 3 was expressed by occasional cells only. Chondrocytes did not express beta 2, beta 3 or other integrin alpha subunits tested.

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Antigens, CDCartilage, ArticularHumansIntegrin beta1IntegrinsJournal ArticleResearch Support, Non-U.S. Gov't

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D M Salter, D E Hughes, R Simpson, D L Gardner. 1992. Integrin expression by human articular chondrocytes.. https://doi.org/10.1093/rheumatology%2F31.4.231

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