PubMed · 13731408
The source did not provide an abstract. Follow the original record for more information.
Explore connections, maps & timelines
E OSETOWSKA, T MANDYBUR. 1961-06-05. [Primary rheumatic encephalitis].. https://pubmed.ncbi.nlm.nih.gov/13731408/
Cite the original work for its findings. Save a collection to share your selection of sources.
KEEP EXPLORING
Intravenous immunoglobulin (IVIG) with high titers to West Nile virus was used as an adjuvant therapy for a patient with West Nile virus encephalitis that did not respond to supportive care. We present this case report and review the evidence supporting the use of high-titer IVIG.
A 53-year-old man presented with optic neuritis, followed within 10 weeks by a subacute progression of weakness, ataxia, and multiple cranial nerve palsies. Cranial magnetic resonance imaging demonstrated multiple T2-hyperintense lesions extending from the ponto-medullary junction to the thalamus and internal capsule. Cerebrospinal fluid analysis showed lymphocytic pleocytosis with elevated protein content. A brain biopsy revealed inflammatory changes. After a month long period of inexorable worsening, the patient was treated with intravenous immunoglobulins (2 g/kg). He responded to treatment, and recovered over the subsequent 3 months. The patient's response to treatment suggests that intravenous immunoglobulins should be considered in patients with inflammatory brain disorders.
Explore the source record for details and available documents.