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Fibroblast growth factor injected in cerebral ventricles does not decrease mean arterial blood pressure.

P Cuevas·F Carceller·I Muñoz-Willery·G Gimenez-Gallego
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Abstract

Intracerebroventricular injections of acidic fibroblast growth factor (aFGF) in rats did not elicit any change in the mean arterial blood pressure, and also did not appreciably affect the hypotensive effect of intravenous injections of aFGF. These observations are of general clinical interest, since such effects could constitute important drawbacks for the therapeutic applications of FGF.

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AnimalsBlood PressureFibroblast Growth Factor 1Injections, IntravenousInjections, IntraventricularRatsRats, Inbred StrainsRecombinant ProteinsJournal ArticleResearch Support, Non-U.S. Gov't

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P Cuevas, F Carceller, I Muñoz-Willery, G Gimenez-Gallego. 1992. Fibroblast growth factor injected in cerebral ventricles does not decrease mean arterial blood pressure.. https://doi.org/10.1097/00001756-199205000-00019

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