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PubMed · 13824160

Decrease in muscle spasm produced by ultrasound, hot packs, and infrared radiation.

F P FOUNTAIN·J W GERSTEN·O SENGIR
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High-Energy Shock WavesHumansNervous System DiseasesPhysical Therapy ModalitiesSpasmPHYSICAL THERAPYSPASM/therapyJournal Article

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F P FOUNTAIN, J W GERSTEN, O SENGIR. 1960. Decrease in muscle spasm produced by ultrasound, hot packs, and infrared radiation.. https://pubmed.ncbi.nlm.nih.gov/13824160/

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RATIONALE AND OBJECTIVES: Many thrombectomy approaches have been developed for the treatment of venous thrombosis; however, no reference standard exists at this time. The aim of this study was to evaluate the efficacy of the transcutaneous application of electrical discharge-induced shock waves for thrombolysis in an in vitro model. METHODS: Shock waves were applied on a thrombus positioned in a plasma-containing silicon tube using 2 different energy flux densities (0.53 and 2.26 mJ/mm). Depending upon the specific experiment, the thrombus was slightly moved to mimic pulsatory motions or/and additional Actilyse was added. Plasma samples were taken to determine the d-dimers before and after the application of shock waves. RESULTS: Energy of 0.53 mJ/mm was insufficient for thrombolysis whereas the energy of 2.26 mJ/mm yielded a removal rate of up to 76.4% when the thrombus was slightly moved during the procedure. The amount of d-dimers correlated well with the addition of Actilyse. However, this did not affect the removal rate significantly. CONCLUSION: The results demonstrate the potential of electrical discharge-induced shock waves for thrombolysis.

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