PubMed · 14028621
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E DONG, E J HURLEY, N E SHUMWAY. 1962. Primary cardiac sarcoma.. https://doi.org/10.1016/0002-9149(62)90186-8
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Positron emission tomography (PET) is a functional diagnostic imaging technique that provides very different information from that obtainable with other imaging modalities. The most widely used radiotracer is F-18 fluoro-2-deoxy-D-glucose (FDG), which is an analog of glucose. The FDG uptake in cells is directly proportional to glucose metabolism, which is increased many times in malignant cells. FDG-PET is now the standard of care in initial staging, monitoring the response to therapy and management of various cancers (e.g., breast cancer, lung cancer and lymphoma). However, the paucity of anatomical landmarks on PET images makes a consistent hardware fusion to anatomical cross-sectional data extremely useful. The introduction of combined PET-computer tomography (CT) scanners, which provide not only functional, but also structural information leading to a detection of subcentimeter lesions, made this technique useful in the early detection of the disease process and decreasing false-positive lesions. The aim of this article is to review the clinical applications (i.e., diagnosis, staging, evaluation of treatment response and restaging) using PET in patients with bone and soft-tissue sarcoma.
Myxofibrosarcoma is common in the extremities, but rare in the head and neck region. Hypopharyngeal myxofibrosarcoma has not been reported previously. We report the first case of a patient with myxofibrosarcoma of the hypopharynx. We examined this patient once a month after the operation, and there has been no local recurrence and no distant metastasis. Sarcomas are rare in the hypopharynx, but we have to bear in mind their possibility. Though a low-grade myxofibrosarcoma is a low-grade malignancy, complete resection should be done. We have to pay more attention planning the treatment for neoplastic diseases.
CASE REPORT: A primary giant infantile fibrosarcoma of the scalp in a 6-month-old boy is reported. He presented with a rapidly enlarging right paramedian parietal scalp swelling since birth. There were no signs of raised intracranial tension. Magnetic resonance (MR) imaging of the brain revealed a large vascular scalp tumor extending over the posterior frontal and parietal region bilaterally crossing the midline. There was no intracranial extension. Carotid angiography revealed an extremely vascular tumor supplied by the external carotid artery branches. The tumor was completely resected through a curvilinear scalp incision. Histology was consistent with diagnosis of an infantile fibrosarcoma. The patient had an uneventful course and received no postoperative adjuvant therapy. MR imaging of the brain at follow-up after 5 years showed no evidence of recurrence of tumor. At follow-up after 10 years, he is asymptomatic and leading an active life. DISCUSSION: The pathology and management of primary scalp fibrosarcoma is discussed, and the relevant literature is briefly reviewed.