Fever responses in newborn lambs.

K Goelst; D Mitchell; H Laburn

doi:10.1007/bf00374215

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Fever responses in newborn lambs.

K Goelst·D Mitchell·H Laburn

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Abstract

Neonatal lambs failed to respond with an increase in body temperature to i.v. injection of both endotoxin (0.4 microgram/kg), a Gram-negative bacterial pyrogen, and the cell walls of Staphylococcus aureus (1 x 10(9), a Gram-positive bacterial pyrogen. However, the fall in serum iron concentration that normally accompanies injection of both the pyrogens in adults was not attenuated in the neonates. We believe that the central nervous system origin of the fever pathway is suppressed in neonatal lambs.

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Animals Animals, Newborn Body Temperature Endotoxins Fever Iron Sheep Staphylococcal Infections Journal Article Research Support, Non-U.S. Gov't

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K Goelst, D Mitchell, H Laburn. 1992. Fever responses in newborn lambs.. https://doi.org/10.1007/bf00374215

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